Organisation/Company CNRS Department Epigénétique et destin cellulaire Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Country France Application Deadline 29 Nov 2024 - 23:59 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Jan 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No
Offer Description Applications are invited for a 3-year postdoctoral position in the laboratory of Dr. Sophie Polo (https://epigenetics.u-paris.fr/polo-group/ ) at the Epigenetics and Cell Fate Centre in Paris. Our research work combines cutting-edge imaging technologies with proteomics and next-generation sequencing to decipher how genome and epigenome maintenance are coordinated in mammalian cells challenged by genotoxic stress.
The proposed postdoctoral work aims at targeting the DNA repair defect that we identified in histone H3 mutant pediatric high-grade glioma (Giacomini et al., Nucleic Acids Res 2024), as part of a collaborative project with the teams of David Castel, Beatrice Rondinelli (Institut Gustave Roussy, Villejuif), Cynthia Hawkins (Sick Children Hospital, Toronto) and Françoise Ochsenbein (I2BC, Saclay).
The successful applicant will join a dynamic research group within a network of six teams working on epigenetics and cell differentiation at the Epigenetics and Cell Fate Centre. This highly vibrant research center is attached to the University Paris Cité, an international and multidisciplinary research environment in central Paris, and offers access to state-of-the-art facilities.
We invite applications from highly self-motivated individuals with a strong interest in chromatin organization, cancer and/or the DNA damage response.
Candidates holding, or shortly expecting to be awarded, a PhD degree in related fields are encouraged to apply. Applicants should have at least one publication as first author.
Interested candidates should provide a CV including publication record, a brief description of their research interests and contacts details for two referees.
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