Psychological sciences » Cognitive science
Psychological sciences » Psychology
Organisation/Company: CNRS Department Institut des Neurosciences Paris-Saclay
Research Field: Neurosciences, Psychological sciences » Cognitive science, Psychological sciences » Psychology
Researcher Profile: Recognised Researcher (R2)
Country: France
Application Deadline: 25 Nov 2024 - 23:59 (UTC)
Type of Contract: Temporary
Job Status: Full-time
Hours Per Week: 35
Offer Starting Date: 1 Apr 2025
Is the job funded through the EU Research Framework Programme? Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure? No
Offer Description To study the postnatal development and ontogeny of sensory, motor, behavioral, cognitive and neuropsychiatric deficits in mouse models of a neurodevelopmental pathology (Duchenne muscular dystrophy). To clarify the differential impact of two mutations leading to distinct neuropsychological profiles in patients. To characterize biochemical biomarkers of the brain cellular alterations associated with these deficits, and the age of onset of these alterations. Use the behavioral phenotypes and biomarkers identified to define an optimal therapeutic window and evaluate the impact of gene therapies aimed at compensating for these deficits.
Postnatal behavior of mice
Dissection and sampling of brain tissue
Biochemical analyses (western blots)
Immunohistochemistry
Confocal imaging
Molecular biology (qPCR)
Intracerebral injections
The position is located at the Institut des Neurosciences Paris Saclay, on the CEA campus, within the Cognition, Plasticity & Neuropathologies team. This team is made up of 14 people (researchers, research professors, engineers and PhD students). The postdoctoral fellow will report directly to the team leader.
The postdoctoral work will be carried out in a dynamic, well-equipped team at the new multidisciplinary Paris-Saclay Neuroscience Institute, in collaboration with a team with long experience of gene therapy. The project is financially supported by the Agence Nationale de la Recherche (ANR, France).
Additional Information Eligibility criteria:
Strong motivation for postnatal behavioral studies in mice, research at the interface between neuroscience and preclinical research, statistics applied to biology, ethics. Organization, rigor, diligence, team spirit, initiative, good writing skills in French and English, fluency in English.
Additional comments Annual leave / RTT: 44 days
- Flexible working hours
- Company restaurant
- Transport: RER B nearby - reimbursement (75% of cost) and sustainable mobility package up to €300
- Social offers: participation in mutual insurance, collective catering, sports and leisure activities, ticketing...
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